Background

We currently live on a planet with other organisms that from a health and wellness perspective, are much further advanced than human beings.

Many lower organisms can replace lost or damaged organs and tissues that are identical in structure and function to the original, effortlessly regenerating a wide variety of tissues, including spinal cords, limbs, hearts, eyes, and even parts of their brains.

In a similar fashion, many of these same species possess fascinating skills for repairing and reversing cellular and genetic damage.  Cancer, as an example, is found to be extremely rare in species displaying an efficient regenerative mechanism, even under the action of potent carcinogens. In many cases, when cancer does occur, tumors have been found to spontaneously remodel and integrate into their surroundings as normal, healthy tissue.

Some of these organisms can age, and then return to a youthful state later on in life.

Some can even die and be reborn.

The Problem

Unfortunately for humans, the situation is very different.  In most instances, the structure or function of an organ will not be restored after tissue damage, and is often replaced by scarring. Additionally, while humans do possess robust DNA repair mechanisms, these capabilities are diminished substantially over time as we age.

Extensive study into the regeneration and repair mechanisms of non-human species have found them to be intricately connected to an underlying capability of complex tissue reprogramming and remodeling.  These capabilities represent a biological regulatory state reset, whereby various forms of damage is erased in cells, followed by their redirection into a developmental program, where they become reintegrated with their micro-environment cellular neighbors, and reorganized via a community effect along tissue, organ and positional specificity.

While many of these species possess these reprogramming and remodeling capabilities throughout their lifetimes, the last and only time at which humans experience such potential is during the brief period following fertilization when egg and sperm first come together to create a new life.  And then it is unfortunately gone.

Bioquark’s mission is to develop novel biologics to re-ignite these capabilities for a variety of therapeutic applications in humans.